| Aug. 21, 2010 | MLS | 2010 | New York Red Bulls | 4 - 1 | Toronto FC | 22108 | 1 | ||
| Aug. 21, 2010 | MLS | 2010 | Los Angeles Galaxy | 0 - 1 | San Jose Earthquakes | 10799 | 1 | ||
| Aug. 21, 2010 | MLS | 2010 | Colorado Rapids | 1 - 3 | Columbus Crew | 16063 | 1 | ||
| Aug. 21, 2010 | MLS | 2010 | Chivas USA | 0 - 1 | FC Dallas | 10309 | 1 | ||
| Aug. 21, 2010 | MLS | 2010 | New England Revolution | 1 - 4 | Kansas City Wizards | 10385 | 1 | ||
| Aug. 21, 2010 | MLS | 2010 | Chicago Fire | 3 - 4 | Houston Dynamo | 18890 | 1 |
| GP | W | T | L | gf | ga | gf/ga | |||
|---|---|---|---|---|---|---|---|---|---|
| LA Galaxy | MLS | 2010 | 21 | 13 | 4 | 4 | 32 | 14 | 2.29 |
| Columbus Crew | MLS | 2010 | 21 | 12 | 4 | 5 | 31 | 20 | 1.55 |
| New York Red Bulls | MLS | 2010 | 21 | 10 | 4 | 7 | 25 | 23 | 1.09 |
| FC Dallas | MLS | 2010 | 20 | 9 | 9 | 2 | 28 | 17 | 1.65 |
| San Jose Earthquakes | MLS | 2010 | 19 | 8 | 5 | 6 | 22 | 20 | 1.10 |
| Colorado Rapids | MLS | 2010 | 20 | 7 | 7 | 6 | 22 | 21 | 1.05 |
| Toronto FC | MLS | 2010 | 20 | 7 | 5 | 8 | 22 | 25 | 0.88 |
| Chicago Fire | MLS | 2010 | 18 | 6 | 6 | 6 | 26 | 26 | 1.00 |
| Houston Dynamo | MLS | 2010 | 21 | 6 | 5 | 10 | 27 | 33 | 0.82 |
| New England Revolution | MLS | 2010 | 20 | 6 | 3 | 11 | 20 | 33 | 0.61 |
| Sporting Kansas City | MLS | 2010 | 20 | 6 | 5 | 9 | 19 | 23 | 0.83 |
| Chivas USA | MLS | 2010 | 20 | 5 | 4 | 11 | 22 | 26 | 0.85 |