| Oct. 4, 2008 | MLS | 2008 | Chivas USA | 3 - 0 | D.C. United | 28145 | 1 | ||
| Oct. 4, 2008 | MLS | 2008 | Columbus Crew | 1 - 0 | Los Angeles Galaxy | 22685 | 1 | ||
| Oct. 4, 2008 | MLS | 2008 | New England Revolution | 2 - 2 | Real Salt Lake | 18893 | 1 | ||
| Oct. 4, 2008 | MLS | 2008 | New York Red Bulls | 1 - 3 | Toronto FC | 13756 | 1 | ||
| Oct. 4, 2008 | MLS | 2008 | Colorado Rapids | 1 - 3 | Houston Dynamo | 12496 | 1 |
| GP | W | T | L | gf | ga | gf/ga | |||
|---|---|---|---|---|---|---|---|---|---|
| Columbus Crew | MLS | 2008 | 27 | 16 | 5 | 6 | 46 | 31 | 1.48 |
| New England Revolution | MLS | 2008 | 27 | 12 | 7 | 8 | 38 | 37 | 1.03 |
| Chivas USA | MLS | 2008 | 27 | 11 | 6 | 10 | 37 | 38 | 0.97 |
| Houston Dynamo | MLS | 2008 | 26 | 11 | 10 | 5 | 39 | 30 | 1.30 |
| Colorado Rapids | MLS | 2008 | 27 | 10 | 4 | 13 | 39 | 40 | 0.98 |
| D.C. United | MLS | 2008 | 27 | 10 | 3 | 14 | 41 | 49 | 0.84 |
| New York Red Bulls | MLS | 2008 | 27 | 9 | 8 | 10 | 36 | 41 | 0.88 |
| Real Salt Lake | MLS | 2008 | 27 | 9 | 8 | 10 | 35 | 36 | 0.97 |
| Toronto FC | MLS | 2008 | 27 | 8 | 7 | 12 | 29 | 37 | 0.78 |
| LA Galaxy | MLS | 2008 | 27 | 7 | 8 | 12 | 50 | 55 | 0.91 |