| Oct. 18, 2008 | MLS | 2008 | Chicago Fire | 2 - 3 | Toronto FC | 20294 | 1 | ||
| Oct. 18, 2008 | MLS | 2008 | Columbus Crew | 1 - 3 | New York Red Bulls | 18546 | 1 | ||
| Oct. 18, 2008 | MLS | 2008 | San Jose Earthquakes | 2 - 3 | Kansas City Wizards | 9841 | 1 | ||
| Oct. 18, 2008 | MLS | 2008 | Houston Dynamo | 3 - 0 | Los Angeles Galaxy | 30361 | 1 | ||
| Oct. 18, 2008 | MLS | 2008 | FC Dallas | 1 - 3 | Real Salt Lake | 17628 | 1 |
| GP | W | T | L | gf | ga | gf/ga | |||
|---|---|---|---|---|---|---|---|---|---|
| Columbus Crew | MLS | 2008 | 29 | 16 | 6 | 7 | 49 | 36 | 1.36 |
| Houston Dynamo | MLS | 2008 | 29 | 13 | 11 | 5 | 44 | 31 | 1.42 |
| Chicago Fire | MLS | 2008 | 29 | 12 | 7 | 10 | 39 | 31 | 1.26 |
| New York Red Bulls | MLS | 2008 | 29 | 10 | 9 | 10 | 40 | 43 | 0.93 |
| Real Salt Lake | MLS | 2008 | 29 | 10 | 9 | 10 | 39 | 38 | 1.03 |
| Sporting Kansas City | MLS | 2008 | 29 | 10 | 9 | 10 | 34 | 38 | 0.89 |
| Toronto FC | MLS | 2008 | 29 | 9 | 8 | 12 | 34 | 41 | 0.83 |
| FC Dallas | MLS | 2008 | 29 | 8 | 11 | 10 | 43 | 39 | 1.10 |
| LA Galaxy | MLS | 2008 | 29 | 8 | 8 | 13 | 53 | 60 | 0.88 |
| San Jose Earthquakes | MLS | 2008 | 29 | 7 | 9 | 13 | 30 | 38 | 0.79 |